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Blue to the sky. Orange to the thigh.

How To Use EpiPen®

The EpiPen® Auto-Injector is a disposable, pre-filled automatic injection device that administers epinephrine in the event of a severe allergic reaction.

Remove the EpiPen® Auto-Injector from the carrier tube and follow these 2 simple steps:

Person pulling blue safety cap off of EpiPen device, “Blue to the sky”
  • Grasp with orange tip pointing downward
  • Remove blue safety cap by pulling straight up – do not bend or twist
Person injecting orange side of EpiPen device into thigh, “Orange to the thigh”
  • Place the orange tip against the middle of the outer thigh
  • Swing and push the auto-injector firmly into the thigh until it “clicks”
  • Hold firmly in place for 3 seconds – count slowly, “1, 2, 3”
EpiPen device after use

Built-in needle protection

After injection, the orange cover automatically extends to ensure the needle is never exposed.

Call 911 after using EpiPen®.

Using EpiPen® does not replace seeing a doctor or going to the hospital.

The effects of epinephrine can wear off or you could have a second reaction, so call 911, or go to the emergency room right after using EpiPen®.

If you or your child do not feel better or get worse you can inject another dose of EpiPen® or EpiPen Jr® 5 to 15 minutes after the first injection.

Do not inject more than 2 injections right after each other.

Too much epinephrine can cause dangerously high blood pressure, stroke, or death. Signs of an overdose include:

  • Irregular heart beat
  • Difficulty breathing caused by a build-up of fluid in your lungs

After getting medical help, stay close to a hospital or where you can easily call 911 for the next 48 hours.

Before leaving the hospital, remember to ask for a new prescription for multiple EpiPen® Auto-Injectors.

Video: How to use EpiPen®

Learn how to properly use EpiPen® and how to practice with your EpiPen® Training Device. Play this video for family and friends to teach them how to use EpiPen® in the event of a severe allergic reaction.

How To Use EpiPen®
On Yourself
Play the how to use EpiPen video