Safety Information

Indications and Clinical Use:
  • EpiPen® and EpiPen Jr® (epinephrine) Auto-Injectors are indicated for the emergency treatment of anaphylactic reactions in patients who are determined to be at increased risk for anaphylaxis, including individuals with a history of anaphylactic reactions.
  • Select dose according to patient’s body weight.
  • Inject into the outer thigh.
  • Following treatment of anaphylaxis, the patient must call 911.

There are no absolute contraindications to the use of epinephrine in a life-threatening allergic situation.

Relevant Warnings and Precautions:
  • Avoid use of epinephrine in patients with cardiogenic, traumatic, or hemorrhagic shock; cardiac dilation; cerebral arteriosclerosis; organic brain damage, and narrow-angle glaucoma
  • Use with caution in patients with cardiac arrhythmias; coronary artery or organic heart disease; hypertension and hyperthyroidism
  • Sulfite sensitivity
  • Diabetes
  • Parkinson’s disease
  • Not intended as a substitute for immediate medical care, the patient should seek immediate medical or hospital care
  • More than two sequential doses of epinephrine should only be administered under direct medical supervision
  • The patient/carer should be informed about the possibility of biphasic anaphylaxis
  • Epinephrine should only be injected into the anterolateral aspect of the thigh. Hold child's leg firmly during injection
  • Suboptimal effect in patients with a thick subcutaneous fat layer
  • Injection site infections
For More Information:

Please consult the prescribing information at for more information relating to adverse reactions, drug interactions, and dosing information, which has not been discussed in this advertisement. The prescribing information is also available by calling 1-800-463-6001.