Safety Information

Indications and Clinical Use:
  • EpiPen® and EpiPen Jr® (epinephrine) Auto-Injectors are indicated for the emergency treatment of anaphylactic reactions in patients who are determined to be at increased risk for anaphylaxis, including individuals with a history of anaphylactic reactions.
  • Select dose according to patient’s body weight.
  • Inject into the outer thigh.
  • Following treatment of anaphylaxis, the patient must call 911.

There are no absolute contraindications to the use of epinephrine in a life-threatening allergic situation.

Relevant Warnings and Precautions:
  • Avoid use of epinephrine in patients with cardiogenic, traumatic, or hemorrhagic shock; cardiac dilation; cerebral arteriosclerosis; organic brain damage, and narrow-angle glaucoma
  • Use with caution in patients with cardiac arrhythmias; coronary artery or organic heart disease; hypertension and hyperthyroidism
  • Sulfite sensitivity
  • Diabetes
  • Parkinson’s disease
  • Not intended as a substitute for immediate medical care, the patient should seek immediate medical or hospital care
  • More than two sequential doses of epinephrine should only be administered under direct medical supervision
  • The patient/carer should be informed about the possibility of biphasic anaphylaxis
  • Epinephrine should only be injected into the anterolateral aspect of the thigh. Hold child's leg firmly during injection
  • Suboptimal effect in patients with a thick subcutaneous fat layer
  • Injection site infections
For More Information:

Please consult the prescribing information at www.pfizer.ca/pm/en/EPIPEN.pdf for more information relating to adverse reactions, drug interactions, and dosing information, which has not been discussed in this advertisement. The prescribing information is also available by calling 1-800-463-6001.