What are the dosing guidelines for the EpiPen® Auto-Injector?

Establish EpiPen^® dosage in any specific patient on body weight. The effective dose is usually in the range of 0.005–0.01 mg/kg body weight.

EpiPen^®:

• The EpiPen^® Auto-Injector is intended for intramuscular administration in adults and children who weigh 30 kg or more.
• The EpiPen^® Auto-Injector delivers a single intramuscular dose of 0.3 mg epinephrine in a 0.3-mL volume (0.3 mg/0.3 mL).

EpiPen Jr^®:

• The EpiPen Jr^® Auto-Injector is intended for pediatric intramuscular administration in children who weigh between 15 kg and 30 kg.
• The EpiPen Jr^® Auto-Injector delivers a single intramuscular dose of 0.15 mg epinephrine in a 0.3-mL volume (0.15 mg/0.3 mL).

Dosing in children (<15 kg):

• Since the dose of epinephrine delivered from EpiPen Jr^® is fixed at 0.15 mg, consider other forms of injectable epinephrine if you feel doses lower than 0.15 mg are necessary (eg, children weighing <15 kg).

Dosing in children (>30 kg):

• The EpiPen^® Auto-Injector 0.3 mg (adult formulation) is recommended.

Dosage adjustments should be made at the discretion of the healthcare provider.